Programme 15-16 November 2019

DAY 1 (Friday, 15th November 2019)

09.20-09.50

Opening ceremony
Peter Falkai, Robert Perneczky, Norbert Müller, LMU Munich / Marion v. Tessin Center

09.50-10.20

Opening presentation: Opportunities and challenges of reserve research
· Yaakov Stern, Columbia University New York 

 

Chair: Enrico Premi, University of Brescia

10.20-10.40

PET imaging in anti-amyloid treatment trials
Timo Grimmer, TU Munich

10.40-11.00

Brain metabolism and cognitive reserve
Matteo Bauckneht, University of Genoa

11.00-11.20

The fronto-parietal control network and its’ role in reserve & resilience
Nicolai Franzmeier, LMU Munich

11.20-11.40

Dynamic connectivity changes in preclinical frontotemporal dementia
Enrico Premi, University of Brescia

11.40-12.00

Protective effects of CSF sTREM2 on cognitive performance 
Michael Ewers, LMU Munich

12.00-13.30

Lunch break

12.00-13.30

Press conference

Chair: Jochen Herms, LMU Munich

13.30-13.50

Cortisol and cognitive function in healthy older adults
Chinedu Udeh-Momoh, Imperial College London

13.50-14.10

BACE1 inhibition and dendritic spines
Jochen Herms, LMU Munich

14.10-14.30

Aβ deposition and microglial response in Alzheimer’s mouse models
Matthias Brendel, LMU Munich

14.30-14.50

Folding mechanisms of alpha-synuclein in vivo
Tim Bartels, University College London

14.50-15.10

BACE1 in neurobiology and Alzheimer’s disease
Stefan Lichtenthaler, TU Munich

15.10-16.10

Coffee break and poster session

Chair: Robert Perneczky, LMU Munich

16.10-16.20

Cerebrospinal fluid biomarkers and cognitive reserve
Panagiotis Alexopoulos, University of Patras

16.20-16.30

Physiological effectiveness of different transcranial stimulation methods (tDCS vs tRNS) in relation to duration of stimulation
Jan Häckert, LMU Munich

16.30-16.40

Motor reserve moderates the detrimental effect of dopamine transporter loss on motor function in Parkinson’s disease
Verana Dzialas, University of Cologne

16.40-16.50

Markers of vitamin B12 status in relation to CSF biomarkers and cognitive performance
Babak Hooshmand, Karolinska Institute Stockholm

16.50-17.00

Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology
Sumali Bajaj, Imperial College London

17.00-17.10

Increased Neuroanatomic Risk for Alzheimer’s Disease Associated with Fine Particle Exposure: Exploring the Role of Cognitive Reserve
Jiu-Chiuan Chen, University of Southern California, Los Angeles

17.10-17.20

The relationship between tau pathology and microglial activation in PSP-Richardson’s syndrome
Maura Malpetti, University of Cambridge

Chair: Michael Ewers, LMU Munich

17.20-17.35

Pro: Appropriate animal models are available
Oliver Wirths, University of Göttingen

17.35-17.50

Con: Better animal models must be developed
Amos Korczyn, Tel Aviv University

17.50-18.00

Discussion and rebuttals

19.30-22.00

Speakers’ dinner
Spatenhaus an der Oper

DAY 2 (Saturday, 16th November 2019)

08.30-08.35

Welcome
Robert Perneczky, Norbert Müller, LMU Munich / Marion v. Tessin Center

Chair: Hans-Jürgen Möller, LMU Munich

08.35-08.55

Clinical aspects of neuroinflammation in Alzheimer’s disease
Norbert Müller, Marion v. Tessin Center 

08.55-09.15

In vivo imaging of glial activation
Magdalena Sastre, Imperial College London 

09.15-09.35

Neuroinflammation in Alzheimer’s disease: the ActiGliA study
Robert Perneczky, LMU Munich 

09.35-09.55

Astroglial imaging in early Alzheimer’s disease
Paul Edison, Imperial College London

09.55-10.15

Inflammasome signalling in neurodegenerative disorders
Michael Heneka, University of Bonn 

10.15-11.00

Special lecture: Microbes and dementia risk
Richard Lathe, University of Edinburgh

11.00-11.25

Coffee break

Chair: Cecilia Samieri, University of Bordeaux

11.25-11.45

The contribution of mid-life activities to late-life cognitive reserve
Richard Henson, University of Cambridge

11.45-12.05

Modulation of genetic risk by lifestyle factors
Arfan Ikram, Erasmus Medical Center Rotterdam

12.05-12.25

Cardiovascular health and dementia risk
Cecilia Samieri, University of Bordeaux

12.25-12.45

Physical activity, apolipoprotein-ɛ4 and multi-domain cognition among healthy older adults
Catherine Robb, Imperial College London

12.45-13.05

Sleep disturbance and dementia risk
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Shireen Sindi, Karolinska Institute Stockholm

13.05-14.00

Lunch break

Chair: Alina Solomon, University of Eastern Finland

14.00-14.20

Biomarkers and response to a multi-modal lifestyle intervention: The FINGER study
Alina Solomon, University of Eastern Finland

14.20-14.40

Challenging neural plasticity in schizophrenia
Alkomiet Hasan, LMU Munich

14.40-15.00

The metabolic brain signature of cognitive resilience
Eider Arenaza-Urquijo, Barcelonabeta Brain Research Center

15.00-15.20

Effects of a 3-Year Multi-Domain Intervention on cognitive performance in older adults with increased dementia risk
Pierre-Jean Ousset, University of Toulouse

15.20-15.40

Functional and structural connectivity changes and their association with lifestyle factors in the DELCODE study
Boris-Stephan Rauchmann, LMU Munich 

15.40-16.00

Closing words and awards presentation
Robert Perneczky, Norbert Müller, LMU Munich / Marion v. Tessin Center

16.00-16.45

Farewell coffee